A new target for deep brain stimulation to reduce arm tremor


  • The posterior subthalamic area (PSA) can be preferable to the traditional thalamic ventral intermediate nucleus (VIM) as a target for deep brain stimulation (DBS), a potent treatment for tremor that is insufficiently improved by medication alone.

Why this matters

  • Although DBS of the VIM is an established alternative to thalamotomy, tremor control has been shown to decrease over time in a proportion of patients.

  • DBS targeting the posterior subthalamic area (PSA-DBS) may provide superior tremor suppression. This potentially leads to other considerations for tremor surgery, e.g. use of modern neuroimaging techniques including tractography to refine the definition of the PSA target.